Recommended Reading to Deepen the Conversation This October
Explore articles hand-selected by Nature editors. Each article has been chosen to give attendees the shared context, relevant background and current research needed to take part in more informed discussions at Meeting the Challenge of Infectious Diseases in a Changing World this October.
Evolution and spillover dynamics of yellow fever at the forest–urban interface in Brazil
Abstract: Yellow fever virus (YFV) continues to threaten human and wildlife populations in the Americas, yet its transmission at the forest–urban interface remains unclear. Ground- and canopy-level mosquito surveillance, systematic monitoring of non-human primate carcasses and viral metagenomics reveal transmission dynamics in metropolitan São Paulo and highlight the importance of multisource surveillance for identifying zoonotic spillover risks.
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A penicillin-binding protein inhibitor series to target drug-resistant Neisseria gonorrhoeae
Abstract: Researchers report a benzoxaborinine-based inhibitor series designed to combat ceftriaxone-resistant gonorrhoea. The lead compound demonstrated potent antibacterial activity, low resistance frequency, favorable safety characteristics and promising efficacy in preclinical studies.
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A global-scale assessment of zoonotic virus diversity and spillover potential in urban-adapted mammal species
Abstract: This global analysis examined urban-adapted mammals and the viruses they carry, identifying hundreds of virus species and highlighting pathways for zoonotic transmission. The findings reinforce the need for enhanced surveillance in urban wildlife populations.
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A deep mutational scanning-informed protein language model predicts SARS-CoV-2 evolution dynamics
Abstract: DeepCoV combines mutational scanning, evolutionary sequence data and epidemiological surveillance to forecast emerging SARS-CoV-2 variants and identify immune-evasive mutations before they become dominant.
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Impact of intensive control on malaria population genomics under elimination settings in Southeast Asia
Abstract: Analysis of more than 2,000 sequenced malaria infections revealed how intensive control measures reshape parasite population structure and provide genomic evidence supporting elimination efforts.
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Strain-level transmission inference across multi-kingdom metagenomic data using TRACS
Abstract: TRACS is a highly accurate algorithm designed to resolve strain-level transmission patterns from metagenomic datasets, improving the understanding of microbial and pathogen spread.
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Long-term HIV-1 remission achieved through allogeneic haematopoietic stem cell transplant
Abstract: This study describes long-term HIV remission in a patient who received a stem cell transplant from a CCR5Δ32/Δ32 donor, providing additional evidence toward potential curative pathways.
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