Ruth Loos is a Vice Executive Director of the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) at the University of Copenhagen and part-time Professor at the Icahn School of Medicine at Mount Sinai, New York. She previously led a research program at the MRC Epidemiology Unit, University of Cambridge, and completed her postdoctoral training at the Pennington Biomedical Research Center in Baton Rouge after earning her PhD from the University of Leuven, Belgium.

Her research focuses on the genetic underpinnings of obesity to uncover the biology of body weight regulation. As a founding member of the GIANT (Genetic Investigation of ANthropometric Traits) consortium, she spearheaded large-scale gene-discovery efforts for BMI and obesity. Beyond traditional measures, her work explores refined adiposity phenotypes and composite traits to reveal biological insights missed by conventional approaches. Leveraging emerging -omics technologies, her team integrates genetic and proteomic data to identify obesity subtypes, predict risk, and inform tailored prevention and treatment strategies.

Ruth leads the Danish Precision Health Initiative (DELPHI), a 25-year longitudinal study of 10,000 individuals in Denmark designed to generate deep, multidimensional health data. DELPHI is an open, collaborative platform that supports dynamic multi-omics research, clinical trials, and innovation through flexible governance and robust infrastructure.

She has served on numerous scientific advisory boards and program committees and was most recently a Board Member of the European Association for the Study of Diabetes (EASD, 2022–2025) and the BioMed Alliance (2024–2025). Ruth is a trustee of European Diabetology. She has held editorial roles for journals including Diabetes, Human Molecular Genetics, PLoS Genetics, eLife, Diabetologia, and Obesity. She has published over 600 papers and holds an H-index of 179.

Laurent Servais MD, PhD is Professor of Pediatric Neuromuscular Diseases at the University of Oxford and Prof of Child Neurology at the University of Liège- Belgium

He is the leader of the pioneering genomic newborn screening project « Babydetect ». He has initiated and led the concept, the validation and the qualification of the first digital outcome measure ever qualified by a regulatory agency.

Marinka Zitnik (https://zitniklab.hms.harvard.edu) is an Associate Professor of Biomedical Informatics at Harvard Medical School, Associate Faculty at Kempner Institute for the Study of Natural and Artificial Intelligence at Harvard University, and Associate Member at Broad Institute of MIT and Harvard. Zitnik investigates foundations of AI that contribute to the scientific understanding of medicine and therapeutic design, eventually enabling AI to learn and innovate on its own. Her research won best paper and research awards, including the Kavli Fellowship of the National Academy of Sciences, Kaneb Fellowship award at Harvard Medical School, NSF CAREER Award, awards from the International Society for Computational Biology, International Conference in Machine Learning, Bayer Early Excellence in Science, Amazon Faculty Research, Google Faculty Research, Roche Alliance with Distinguished Scientists, and Sanofi iDEA-iTECH Award. Zitnik founded Therapeutics Data Commons, a global open-science initiative to access and evaluate AI across stages of development and therapeutic modalities, and she served as the faculty lead of the AI4Science initiative.

Dr. Nigam Shah is Professor of Medicine at Stanford University and Chief Data Scientist for Stanford Health Care. He is a world-renowned scientist and entrepreneur with deep expertise in applying machine learning and artificial intelligence (AI) to analyze diverse health data, including electronic health records, claims, and wearables. In his Chief Data Scientist role, he oversees the responsible use of AI for advancing disease understanding and improving clinical care delivery across Stanford Health Care. In 2018, he created the USA's only bedside consultation service, to provide clinicians with on-demand patient outcome summaries. This service was cited in Congressional testimony and was  spun out as the independent company Atropos Health in 2021.

Shah's research is highly influential, with over 350 publications (h-index 94) in journals such as JAMA and the New England Journal of Medicine, receiving over 43,000 citations. As an entrepreneur, he holds nine patents and co-founded three companies that collectively raised over $100 million. He is a dedicated educator, teaching in multiple graduate classes at Stanford University and in an AI in Healthcare Specialization to over 60,000 students online. He is a member of the National Academy of Medicine’s Digital Learning Collaborative as well as a cofounder of the coalition for health AI, which provides guidelines for the responsible use of AI in healthcare.

Dr. Chris Tomlinson is a Clinician Scientist and AI+ Academic Senior Fellow (Associate Professor) at King’s College London. With a clinical background in Anaesthetics and Intensive Care, his work leverages electronic health records, epidemiology and artificial intelligence at scale to advance our understanding of health and disease, address the fundamental challenges of precision medicine and enable people to live healthier lives.

As Principal Investigator for Foresight-England, Dr. Tomlinson led the development of a world-first population-scale generative AI model of electronic health records from 57 million individuals. His research portfolio also includes pioneering work on proteomic machine learning for drug discovery and early detection of disease, building clinically-aligned generative AI for tasks such as discharge summarisation, as well as leading national-scale informatics and epidemiology projects that generated critical evidence during the COVID pandemic. His work has informed global policy and clinical guidelines, with publications in leading journals and conferences such as Nature Medicine, The BMJ, The Lancet Digital Health, NeurIPS and AAAI.

Eran Segal is a Professor at Mohamed Bin Zayed University of Artificial Intelligence and at the Weizmann Institute of Science, heading a lab with a multi-disciplinary team of computational biologists and experimental scientists in the area of Computational and Systems biology. His group has extensive experience in AI, machine learning, computational biology, and analysis of heterogeneous high-throughput genomic data. His research explores the links between the microbiome, nutrition, genetics, and other clinical, physiological, and multi-omic phenotypes on human health, aiming to develop personalized medicine by analyzing large-scale and deeply phenotyped human cohorts.  

Prof. Segal published over 250 publications that were cited over 85,000 times (H-index: 115), and received several awards and honors for his work, including the Overton prize, awarded annually by the International Society for Bioinformatics (ICSB) to one scientist for outstanding accomplishments in computational biology, and the Michael Bruno award. He was also elected as an EMBO member and as a member of the young Israeli academy of science. During the COVID-19 pandemic, Prof. Segal developed models for analyzing the dynamics of the pandemic and served as a senior advisor to the government of Israel. 

Before joining the Weizmann Institute, Prof. Segal held an independent research position at Rockefeller University, New York. 

Education: Prof. Segal was awarded a B.Sc. in Computer Science summa cum laude in 1998, from Tel-Aviv University, and a Ph.D. in Computer Science and Genetics in 2004, from Stanford University.

Dr. Josh Denny, M.D., M.S., is the Chief Executive Officer of the National Institutes of Health’s All of Us Research Program, a nationwide health research program that has already enrolled more than 860,000 participants. All of Us has created one of the world’s largest biomedical data sets that more than 18,000 researchers use to improve medical care through personalized insights and scientific discovery. Dr. Denny, who was named CEO in January 2020, led the program’s initial prototyping project and the All of Us Data and Research Center. 

Prior to joining NIH, Dr. Denny held leadership positions at Vanderbilt University Medical Center, where he pioneered the use of electronic health records for genomics studies, including phenome-wide association studies and clinical pharmacogenomics. He is an elected member of the National Academy of Medicine, the American Society for Clinical Investigation, and a fellow of the American College of Medical Informatics. Dr. Denny has authored over 400 peer-reviewed publications.